71686-01-6
71686-01-6
Chemical Structure
Calcium 2-oxoglutarate
- CAS No.: 71686-01-6
- Formula:C5H4CaO5
- Molecular Weight:184.16
IUPAC Name: calcium 2-oxopentanedioate
InChIKey: LADYPAWUSNPKJF-UHFFFAOYSA-L
SMILES: O=C([O-])C(CCC([O-])=O)=O.[Ca+2]
Biological Activity: Calcium 2-oxoglutarate is an intermediate in the production of ATP or GTP in the Krebs cycle. Calcium 2-oxoglutarate also acts as the major carbon skeleton for nitrogen-assimilatory reactions. Calcium 2-oxoglutarate is a reversible inhibitor of tyrosinase (IC50=15 mM)[1][2].
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Calcium 2-oxoglutarate | 98.0% | Calcium 2-oxoglutarate is an intermediate in the production of ATP or GTP in the Krebs cycle. Calcium 2-oxoglutarate also acts as the major carbon skeleton for nitrogen-assimilatory reactions. Calcium 2-oxoglutarate is a reversible inhibitor of tyrosinase (IC50=15 mM). | ||||||||||||||||||||
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Calcium 2-oxoglutarate (Standard) | ≥98% | Calcium 2-oxoglutarate (Standard) is the analytical standard of Calcium 2-oxoglutarate (HY-W013636B). This product is intended for research and analytical applications. Calcium 2-oxoglutarate is an intermediate in the production of ATP or GTP in the Krebs cycle. Calcium 2-oxoglutarate also acts as the major carbon skeleton for nitrogen-assimilatory reactions. Calcium 2-oxoglutarate is a reversible inhibitor of tyrosinase (IC50=15 mM). | ||||||||||||||||||||
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References
- [1]. Huergo LF, et al. The Emergence of 2-Oxoglutarate as a Master Regulator Metabolite. Microbiol Mol Biol Rev. 2015 Dec;79(4):419-35. [Content Brief]
- [2]. Gou L, et al. The effect of alpha-ketoglutaric acid on tyrosinase activity and conformation: Kinetics and molecular dynamics simulation study. Int J Biol Macromol. 2017 Dec;105(Pt 3):1654-1662. [Content Brief]
