717899-97-3

CE-245677 Chemical Structure
717899-97-3

Chemical Structure

CE-245677

  • CAS No.: 717899-97-3
  • Formula:C24H22Cl2N6O3
  • Molecular Weight:513.38

IUPAC Name: 1-(5-(4-amino-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-2-methoxyphenyl)-3-(2,4-dichlorophenyl)urea

InChIKey: VFCRSIORGUNNGT-UHFFFAOYSA-N

SMILES: O=C(NC1=CC=C(Cl)C=C1Cl)NC2=CC(C(C3=CN(C(C)C)C4=NC=NC(N)=C43)=O)=CC=C2OC

Biological Activity: CE-245677 is a potent reversible inhibitor of Tie2 and TrkA/B kinases with a cellular IC50s of 4.7 and 1 nM.

Cat. No. Product Name Purity Description Pricing
HY-112423
CE-245677 98.00% CE-245677 is a potent reversible inhibitor of Tie2 and TrkA/B kinases with a cellular IC50s of 4.7 and 1 nM.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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