73183-34-3
Chemical Structure
Bis(pinacolato)diborane
- CAS No.: 73183-34-3
- Formula:C12H24B2O4
- Molecular Weight:253.94
IUPAC Name: 4,4,4',4',5,5,5',5'-octamethyl-2,2'-bi(1,3,2-dioxaborolane)
InChIKey: IPWKHHSGDUIRAH-UHFFFAOYSA-N
SMILES: CC1(C)C(C)(C)OB(B2OC(C)(C)C(C)(C)O2)O1
Biological Activity: Bis(pinacolato)diborane is an organoboron reagent. Bis(pinacolato)diborane serves as a source of the [Bpin] moiety with pronounced nucleophilic character and is used in the synthesis of various organoboranes, including organoboron compounds and arylboronates[1][2][3].Bis(pinacolato)diborane reacts with p-benzyne to produce tetraborylated products through a series of steps involving addition and 1,2-migration of the boryl group[2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Bis(pinacolato)diborane | 99.90% | Bis(pinacolato)diborane is an organoboron reagent. Bis(pinacolato)diborane serves as a source of the [Bpin] moiety with pronounced nucleophilic character and is used in the synthesis of various organoboranes, including organoboron compounds and arylboronates.Bis(pinacolato)diborane reacts with p-benzyne to produce tetraborylated products through a series of steps involving addition and 1,2-migration of the boryl group. | ||||||||||||||||||||
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1β,4β,7α-Trihydroxyeudesmane | 1β,4β,7α-Trihydroxyeudesmane (compound 4) is a nature product that could be isolated from the rhizomes of Homalomena occulta. 1β,4β,7α-Trihydroxyeudesmane has antiproliferative active. 1β,4β,7α-Trihydroxyeudesmane can be used in research of cancer. | |||||||||||||||||||||
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Teuclatriol | Teuclatriol is an NF-κB inhibitor can be isolated from salvia mirzayanii, has anti-inflammatory effects. Teuclatriol inhibits TNF-α secretion in a dose-dependent manner. | |||||||||||||||||||||
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10-Epiteuclatriol | 10-Epiteuclatriol is a natural product. | |||||||||||||||||||||
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Ambroxdiol | Ambroxdiol is a diterpenoid compound with anti-inflammatory activity. Ambroxdiol can be used as an active ingredient in the preparation of preparations for inhibiting inflammatory responses, and can also be used as an anti-inflammatory ingredient in cosmetic preparations for skin and mucous membrane care. Ambroxdiol is applicable to the research of inflammatory diseases. | |||||||||||||||||||||
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Pterodondiol | Pterodondiol is a gandular trichome metabolite on the leaves of Laggera pterodonta. | |||||||||||||||||||||
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Reneilmol | Reneilmol is a natural sesquiterpene. | |||||||||||||||||||||
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Cryptomeridiol | Cryptomeridiol is a platelet-activating factor (PAF) receptor binding inhibitor. Cryptomeridiol has melanogenesis inhibitory activity in the α-MSH (HY-P0252)-stimulated B16 melanoma cells. | |||||||||||||||||||||
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Sclareol glycol (Standard) | ≥98% | Sclareol glycol (Standard) is the analytical standard of Sclareol glycol (HY-N7007). This product is intended for research and analytical applications. Sclareol glycol is a blood-brain barrier-permeable, reversible adenylate cyclase (AC) activator. Sclareol glycol induces dose-dependent changes in body temperature, regulates convulsive seizures and spontaneous activity. Sclareol glycol interacts with GABAergic transmission, thereby affecting dopamine-related behaviors. Sclareol glycol can be used in studies related to convulsive seizures, aggressive responses, thermoregulation, etc. | ||||||||||||||||||||
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4-Hydroxyphenylboronic acid pinacol ester | 99.72% | 4-Hydroxyphenylboronic acid pinacol ester is a ROS-responsive component. 4-Hydroxyphenylboronic acid pinacol ester can structurally modify hyaluronic acid to prepare ROS-responsive intelligent nanocarriers and compound delivery systems. 4-Hydroxyphenylboronic acid pinacol ester endows hyaluronic acid-based nanocarriers with ROS responsiveness, enabling them to rapidly release the encapsulated Curcumin (HY-N0005) in the presence of reactive oxygen species. 4-Hydroxyphenylboronic acid pinacol ester is applicable to research related to periodontitis. 4-Hydroxyphenylboronic acid pinacol ester can also be used for the synthesis of boronic acid-modified resins. | ||||||||||||||||||||
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trans-1-Octen-1-ylboronic acid pinacol ester | trans-1-Octen-1-ylboronic acid pinacol ester (trans-TMOE) is a biochemical reagent. | |||||||||||||||||||||
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References
- [1]. Pécharman AF, et al. Easy access to nucleophilic boron through diborane to magnesium boryl metathesis. Nat Commun. 2017;8:15022. Published 2017 Apr 7. [Content Brief]
- [2]. Nakatsuka S, et al. Tetraborylation of p-Benzynes Generated by the Masamune-Bergman Cyclization through Reaction Design Based on the Reaction Path Network. JACS Au. 2024;4(7):2578-2584. Published 2024 Jun 20. [Content Brief]
- [3]. VALERY M DEMBITSKY, et al. Recent Chemistry of the Diboron Compounds. Advances in Organometallic Chemistry. Volume 51, 2004, Pages 193-250.