73257-80-4
73257-80-4
Chemical Structure
PDMP hydrochloride
- CAS No.: 73257-80-4
- Formula:C23H39ClN2O3
- Molecular Weight:N/A
SMILES: CCCCCCCCCC(NC(CN1CCOCC1)C(C2=CC=CC=C2)O)=O.[x].Cl
Biological Activity: PDMP hydrochloride is a glucosylceramide synthase (GCS) inhibitor. PDMP hydrochloride induces apoptosis in K562/A02 cells. PDMP hydrochloride can be used in cancer (such as leukemia) research[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PDMP hydrochloride | 99.9% | PDMP hydrochloride is a glucosylceramide synthase (GCS) inhibitor. PDMP hydrochloride induces apoptosis in K562/A02 cells. PDMP hydrochloride can be used in cancer (such as leukemia) research. | ||||||||||||||||||||
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References
- [1]. Casson L, et al. Inhibition of ceramide metabolism sensitizes human leukemia cells to inhibition of BCL2-like proteins. PLoS One. 2013;8(1):e54525. [Content Brief]
- [2]. Yin L, et al. Effect of PDMP, a glucosylceramide synthase inhibitor, on reversion of daunorubicin resistance in human leukemia cell line K562/A02. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2010 Feb;18(1):79-84. [Content Brief]
