733805-92-0
Chemical Structure
Orniplabin
Synonym(s): SMTP-7
- CAS No.: 733805-92-0
- Formula:C51H68N2O10
- Molecular Weight:869.09
IUPAC Name: (S)-2,5-bis((2S,3S)-2-((E)-4,8-dimethylnona-3,7-dien-1-yl)-3,5-dihydroxy-2-methyl-7-oxo-3,4,7,9-tetrahydropyrano[2,3-e]isoindol-8(2H)-yl)pentanoic acid
InChIKey: CRNDCHORWGDFGR-PXTWCNKMSA-N
SMILES: O=C1C2=C(C3=C(C[C@H](O)[C@@](CC/C=C(C)/CC/C=C(C)/C)(C)O3)C(O)=C2)CN1[C@H](C(O)=O)CCCN4CC5=C(C=C(O)C6=C5O[C@](CC/C=C(C)/CC/C=C(C)/C)(C)[C@@H](O)C6)C4=O
Biological Activity: Orniplabin (SMTP-7) is a plasminogen modulator with a human EC50 of 65 μM. Orniplabin enhances activation of plasminogen by plasminogen activators and increases fibrin-binding of plasminogen. Orniplabin elevates plasma levels of plasmin-α2-antiplasmin complex in vivo. Orniplabin can be used for the research of pulmonary embolism, thrombotic stroke[1].
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Orniplabin | Orniplabin (SMTP-7) is a plasminogen modulator with a human EC50 of 65 μM. Orniplabin enhances activation of plasminogen by plasminogen activators and increases fibrin-binding of plasminogen. Orniplabin elevates plasma levels of plasmin-α2-antiplasmin complex in vivo. Orniplabin can be used for the research of pulmonary embolism, thrombotic stroke. | |||||||||||||||||||||
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