74050-20-7
Chemical Structure
Hydrocortisone aceponate
Synonym(s): Hydrocortisone 17-propionate 21-acetate
- CAS No.: 74050-20-7
- Formula:C26H36O7
- Molecular Weight:460.56
IUPAC Name: (8S,9S,10R,11S,13S,14S,17R)-17-(2-acetoxyacetyl)-11-hydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl propionate
InChIKey: MFBMYAOAMQLLPK-FZNHGJLXSA-N
SMILES: C[C@@]12[C@](OC(CC)=O)(CC[C@]1([C@@]3(CCC4=CC(CC[C@@]4([C@]3([C@H](C2)O)[H])C)=O)[H])[H])C(COC(C)=O)=O
Biological Activity: Hydrocortisone aceponate (Hydrocortisone 17-propionate 21-acetate) is a diester-based topical glucocorticoid. Hydrocortisone aceponate alleviates symptoms such as erythema, dryness/desquamation, pruritus, epidermal exfoliation, and exudation/crusting. Hydrocortisone aceponate causes extremely few adverse reactions. Hydrocortisone aceponate is applicable to various dermatological disease studies[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Hydrocortisone aceponate | 99.43% | Hydrocortisone aceponate (Hydrocortisone 17-propionate 21-acetate) is a diester-based topical glucocorticoid. Hydrocortisone aceponate alleviates symptoms such as erythema, dryness/desquamation, pruritus, epidermal exfoliation, and exudation/crusting. Hydrocortisone aceponate causes extremely few adverse reactions. Hydrocortisone aceponate is applicable to various dermatological disease studies. | ||||||||||||||||||||
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Hydrocortisone aceponate (Standard) | ≥98% | Hydrocortisone aceponate (Hydrocortisone 17-propionate 21-acetate) Standard is the analytical standard of Hydrocortisone aceponate (HY-116691). This product is intended for research and analytical applications. Hydrocortisone aceponate (Hydrocortisone 17-propionate 21-acetate) is a diester-based topical glucocorticoid. Hydrocortisone aceponate alleviates symptoms such as erythema, dryness/desquamation, pruritus, epidermal exfoliation, and exudation/crusting. Hydrocortisone aceponate causes extremely few adverse reactions. Hydrocortisone aceponate is applicable to various dermatological disease studies. | ||||||||||||||||||||
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References
- [1]. Rème C A, et al. Effects of repeated topical application of a 0.0584% hydrocortisone aceponate spray on skin thickness in beagle dogs[J]. International Journal of Applied Research in Veterinary Medicine, 2010, 8: 1-6.
- [2]. Mukhopadhyay AK, et al. A study to evaluate the efficacy and safety of hydrocortisone aceponate 0.127% lipophilic cream in steroid responsive dermatoses in Indian patients. Indian J Dermatol Venereol Leprol. 2010;76(5):591. [Content Brief]
