740841-15-0
740841-15-0
Chemical Structure
(E/Z)-BIO-acetoxime
Synonym(s): GSK-3 Inhibitor X
- CAS No.: 740841-15-0
- Formula:C18H12BrN3O3
- Molecular Weight:398.21
IUPAC Name: (2E,3E)-3-(acetoxyimino)-6'-bromo-[2,3'-biindolinylidene]-2'-one
InChIKey: MENDIXKFTXYTHJ-TWNGPSNKSA-N
SMILES: CC(O/N=C1/C(NC2=C1C=CC=C2)=C3C(NC4=C\3C=CC(Br)=C4)=O)=O
Biological Activity: (E/Z)-BIO-acetoxime (GSK-3 Inhibitor X) is a potent and selective GSK-3α/β inhibitor, with an IC50 of 10 nM. (E/Z)-BIO-acetoxime shows more than 200-flod selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B (IC50=2.4, 4.3, 63 μM)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(E/Z)-BIO-acetoxime | 99% | (E/Z)-BIO-acetoxime (GSK-3 Inhibitor X) is a potent and selective GSK-3α/β inhibitor, with an IC50 of 10 nM. (E/Z)-BIO-acetoxime shows more than 200-flod selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B (IC50=2.4, 4.3, 63 μM). | ||||||||||||||||||||
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