742058-34-0
742058-34-0
Chemical Structure
Nurr1 agonist 2
- CAS No.: 742058-34-0
- Formula:C18H14O3S
- Molecular Weight:310.37
IUPAC Name: 5-(4-(benzyloxy)phenyl)thiophene-2-carboxylic acid
InChIKey: BRNQGIMGJSDTMI-UHFFFAOYSA-N
SMILES: OC(C1=CC=C(C2=CC=C(C=C2)OCC3=CC=CC=C3)S1)=O
Biological Activity: Nurr1 agonist 2 (Compound 7) is a Nurr1 agonist (EC50: 0.07 μM). Nurr1 agonist 2 binds to the recombinant Nurr1 ligand binding domain (LBD) with a Kd value of 0.14 μM. Nurr1 agonist 2 increases the Nurr1-regulated genes tyrosine hydroxylase (TH) and vesicular amino acid transporter 2 (VMAT2) mRNA expression[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Nurr1 agonist 2 | 98.03% | Nurr1 agonist 2 (Compound 7) is a Nurr1 agonist (EC50: 0.07 μM). Nurr1 agonist 2 binds to the recombinant Nurr1 ligand binding domain (LBD) with a Kd value of 0.14 μM. Nurr1 agonist 2 increases the Nurr1-regulated genes tyrosine hydroxylase (TH) and vesicular amino acid transporter 2 (VMAT2) mRNA expression. | ||||||||||||||||||||
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