74517-78-5
74517-78-5
Chemical Structure
Indecainide
Synonym(s): Ricainide; LY 135837 free base
- CAS No.: 74517-78-5
- Formula:C20H24N2O
- Molecular Weight:308.42
IUPAC Name: 9-(3-(isopropylamino)propyl)-9H-fluorene-9-carboxamide
InChIKey: UCEWGESNIULAGX-UHFFFAOYSA-N
SMILES: O=C(N)C1(C2=C(C=CC=C2)C3=C1C=CC=C3)CCCNC(C)C
Biological Activity: Indecainide (Ricainide) is an orally active antiarrhythmic agent. Indecainide can be used in the research of ventricular dysfunction. Indecainide has Na+-channel-blocking activity[1][2].
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Indecainide | Indecainide (Ricainide) is an orally active antiarrhythmic agent. Indecainide can be used in the research of ventricular dysfunction. Indecainide has Na+-channel-blocking activity. | |||||||||||||||||||||
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References
- [1]. D R Holland, et al. Indecainide: effects on arrhythmias, electrophysiology, and cardiovascular dynamics. J Cardiovasc Pharmacol. 1989 Sep;14(3):454-61. [Content Brief]
- [2]. Lindstrom T D, et al. Metabolism of the antiarrhythmic agent, indecainide, in rats, dogs, and monkeys. Drug metabolism and disposition, 1984, 12(6): 691-697. [Content Brief]
