7469-49-0
7469-49-0
Chemical Structure
Nav1.2-IN-2
- CAS No.: 7469-49-0
- Formula:C17H26N2O4
- Molecular Weight:322.40
InChIKey: KOBZWUMLQLKNMP-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(C)C(NC(OCCCC)=O)=C1)OCCCC
Biological Activity: Nav1.2-IN-2 is a Nav1.2 inhibitor with a human IC50 of 0.18 μM. Nav1.2-IN-2 preferentially binds to the inactivated state of Nav1.2, reduces window current, suppresses neuronal depolarization and action potential generation. Nav1.2-IN-2 suppresses Veratridine (HY-N6691)-induced Ca2+ influx. Nav1.2-IN-2 can be used for the research of epilepsy[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Nav1.2-IN-2 | 99.82% | Nav1.2-IN-2 is a Nav1.2 inhibitor with a human IC50 of 0.18 μM. Nav1.2-IN-2 preferentially binds to the inactivated state of Nav1.2, reduces window current, suppresses neuronal depolarization and action potential generation. Nav1.2-IN-2 suppresses Veratridine (HY-N6691)-induced Ca2+ influx. Nav1.2-IN-2 can be used for the research of epilepsy. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
