75144-12-6
75144-12-6
Chemical Structure
Antitrypanosomal agent 1
- CAS No.: 75144-12-6
- Formula:C11H14Cl3NO
- Molecular Weight:282.59
IUPAC Name: 1-(3,4-dichlorophenyl)-3-(dimethylamino)propan-1-one hydrochloride
InChIKey: PRRKQCKNKRZOPV-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(Cl)C(Cl)=C1)CCN(C)C.[H]Cl
Biological Activity: Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor with an IC50 of 3.3 μM. Antitrypanosomal agent 1 inhibits glutathione reductase (GR) (IC50=64.8 μM) and T. brucei (EC50=1 μM). Antitrypanosomal agent 1 has anti-trypanosomal activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Antitrypanosomal agent 1 | 99.50% | Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor with an IC50 of 3.3 μM. Antitrypanosomal agent 1 inhibits glutathione reductase (GR) (IC50=64.8 μM) and T. brucei (EC50=1 μM). Antitrypanosomal agent 1 has anti-trypanosomal activity. | ||||||||||||||||||||
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