760944-56-7
Chemical Structure
BMS-604992 free base
Synonym(s): EX-1314 free base
- CAS No.: 760944-56-7
- Formula:C24H31N7O5
- Molecular Weight:497.55
IUPAC Name: (S)-(3-(1-(2-amino-2-methylpropanamido)-2-(benzyloxy)ethyl)-[1,2,4]triazolo[4,3-a]pyridin-5-yl)methyl (2-amino-2-oxoethyl)(methyl)carbamate
InChIKey: HXOYZOFSGAXBOH-GOSISDBHSA-N
SMILES: O=C(OCC1=CC=CC2=NN=C([C@H](NC(C(C)(N)C)=O)COCC3=CC=CC=C3)N12)N(CC(N)=O)C
Biological Activity: BMS-604992 (EX-1314) free base is a selective, orally active small-molecule growth hormone secretagogue receptor (GHSR) agonist. BMS-604992 free base demonstrates high-affinity binding (ki=2.3 nM) and potent functional activity (EC50=0.4 nM). BMS-604992 free base can stimulate food intake in rodents[1].
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BMS-604992 free base | BMS-604992 (EX-1314) free base is a selective, orally active small-molecule growth hormone secretagogue receptor (GHSR) agonist. BMS-604992 free base demonstrates high-affinity binding (ki=2.3 nM) and potent functional activity (EC50=0.4 nM). BMS-604992 free base can stimulate food intake in rodents. | |||||||||||||||||||||
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