76496-68-9
Chemical Structure
R-(-)-Oxaprotiline
Synonym(s): Levoprotiline
- CAS No.: 76496-68-9
- Formula:C20H23NO
- Molecular Weight:293.40
IUPAC Name: (R)-1-(9,10-ethanoanthracen-9(10H)-yl)-3-(methylamino)propan-2-ol
InChIKey: FDXQKWSTUZCCTM-ZUIJCZDSSA-N
SMILES: O[C@H](CC12C3=C(C(C4=CC=CC=C24)CC1)C=CC=C3)CNC
Biological Activity: R-(-)-Oxaprotiline (Levoprotiline) is an antidepressant with anticholinergic and sympathostimulatory activities. R-(-)-Oxaprotiline exhibits different abilities to block norepinephrine uptake and anticholinergic activity compared to its enantiomer C 49802 B-Ba. R-(-)-Oxaprotiline in human studies shows physiological effects consistent with those in animals. Administration of R-(-)-Oxaprotiline results in a modest increase in heart rate and arterial blood pressure. Salivation is inhibited with R-(-)-Oxaprotiline, consistent with its anticholinergic properties. R-(-)-Oxaprotiline has similar effects to the established antidepressant compound Levoprotiline and has a shorter onset of action[1].
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R-(-)-Oxaprotiline | R-(-)-Oxaprotiline (Levoprotiline) is an antidepressant with anticholinergic and sympathostimulatory activities. R-(-)-Oxaprotiline exhibits different abilities to block norepinephrine uptake and anticholinergic activity compared to its enantiomer C 49802 B-Ba. R-(-)-Oxaprotiline in human studies shows physiological effects consistent with those in animals. Administration of R-(-)-Oxaprotiline results in a modest increase in heart rate and arterial blood pressure. Salivation is inhibited with R-(-)-Oxaprotiline, consistent with its anticholinergic properties. R-(-)-Oxaprotiline has similar effects to the established antidepressant compound Levoprotiline and has a shorter onset of action. | |||||||||||||||||||||
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