76931-93-6
Chemical Structure
N-Succinimidyl-S-acetylthioacetate
Synonym(s): SATA
- CAS No.: 76931-93-6
- Formula:C8H9NO5S
- Molecular Weight:231.23
IUPAC Name: 2,5-dioxopyrrolidin-1-yl 2-(acetylthio)acetate
InChIKey: FLCQLSRLQIPNLM-UHFFFAOYSA-N
SMILES: O=C(ON1C(CCC1=O)=O)CSC(C)=O
Biological Activity: N-Succinimidyl S-acetylthioacetate (SATA) is a protein modifying agent. N-Succinimidyl S-acetylthioacetate adds sulfhydryl groups to proteins and other amine-containing molecules in a protected form. N-Succinimidyl-S-acetylthioacetate can thiolate antibodies, thereby promoting efficient attachment of antibodies to other molecules and exerting conjugation activity. N-Succinimidyl-S-acetylthioacetate can be used in immunoassays such as ELISA studies[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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N-Succinimidyl-S-acetylthioacetate | 99.56% | N-Succinimidyl S-acetylthioacetate (SATA) is a protein modifying agent. N-Succinimidyl S-acetylthioacetate adds sulfhydryl groups to proteins and other amine-containing molecules in a protected form. N-Succinimidyl-S-acetylthioacetate can thiolate antibodies, thereby promoting efficient attachment of antibodies to other molecules and exerting conjugation activity. N-Succinimidyl-S-acetylthioacetate can be used in immunoassays such as ELISA studies. | ||||||||||||||||||||
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References
- [1]. J.L.M.Heeremans, et al. Interference of ϵ-amino-caproic acid with [N-succinimidyl S-acetylthioacetate derived] thiol-introduction into glu-plasminogen. Volume 8, Supplement 2, 1994, Pages 138-141.
- [2]. Allen KJH, et al. Evaluation of N-Succinimidyl S-Acetylthioacetate Ligand for Radiolabeling of HumanizedAntibodies with 188Rhenium. Cancer Biother Radiopharm. 2018 Oct;33(8):349-355. [Content Brief]
- [3]. Nanda S, et al. Thermostable alpha-amylase conjugated antibodies as probes for immunodetection in ELISA. J Immunoassay Immunochem. 2002;23(3):327-45. [Content Brief]
