76939-42-9
76939-42-9
Chemical Structure
Luteolin-7-O-β-D-glucuronide methyl ester
- CAS No.: 76939-42-9
- Formula:C22H20O12
- Molecular Weight:476.39
InChIKey: VQDVPEBDINWLHZ-SXFAUFNYSA-N
SMILES: O=C1C2=C(O)C=C(O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)C(OC)=O)C=C2OC(C4=CC(O)=C(C=C4)O)=C1
Biological Activity: Luteolin-7-O-β-D-glucuronide methyl ester is a flavonoid with antioxidative activity. Luteolin-7-O-β-D-glucuronide methyl ester exhibits potent antioxidative activity with an IC50 of 3.05 μg/mL in the NBT superoxide scavenging assay. Luteolin-7-O-β-D-glucuronide methyl ester inhibits LDL oxidation induced by Cu2+ with the IC50 value is 71.13 μg/mL[1][2].
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Luteolin-7-O-β-D-glucuronide methyl ester | Luteolin-7-O-β-D-glucuronide methyl ester is a flavonoid with antioxidative activity. Luteolin-7-O-β-D-glucuronide methyl ester exhibits potent antioxidative activity with an IC50 of 3.05 μg/mL in the NBT superoxide scavenging assay. Luteolin-7-O-β-D-glucuronide methyl ester inhibits LDL oxidation induced by Cu2+ with the IC50 value is 71.13 μg/mL. | |||||||||||||||||||||
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References
- [1]. Woo ER, et al. Antioxidative constituents from Lycopus lucidus. Arch Pharm Res. 2004 Feb;27(2):173-6. [Content Brief]
- [2]. Lee MJ, et al. Protective effects of luteolin-7-O-beta-D-glucuronide methyl ester from the ethyl acetate fraction of Lycopi Herba against pro-oxidant reactive species and low-density lipoprotein peroxidation. J Enzyme Inhib Med Chem. 2010 Oct;25(5):702-7. [Content Brief]
