77133-35-8
77133-35-8
Chemical Structure
1-O-Hexadecyl-2-O-acetyl-sn-glycerol
- CAS No.: 77133-35-8
- Formula:C21H42O4
- Molecular Weight:358.56
IUPAC Name: (S)-1-(hexadecyloxy)-3-hydroxypropan-2-yl acetate
InChIKey: QTEHGUUSIIWOOW-NRFANRHFSA-N
SMILES: CCCCCCCCCCCCCCCCOC[C@H](CO)OC(C)=O
Biological Activity: 1-O-Hexadecyl-2-O-acetyl-sn-glycerol is an alkyl acylglycerol that may activate the amino acid transport activity of the A-system and stimulate the absorption of methylaminoisobutyric acid (MeAIB). MeAIB inhibits mTOR phosphorylation, which may affect intestinal amino acid absorption and signal transduction[1][2].
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1-O-Hexadecyl-2-O-acetyl-sn-glycerol | 1-O-Hexadecyl-2-O-acetyl-sn-glycerol is an alkyl acylglycerol that may activate the amino acid transport activity of the A-system and stimulate the absorption of methylaminoisobutyric acid (MeAIB). MeAIB inhibits mTOR phosphorylation, which may affect intestinal amino acid absorption and signal transduction. | |||||||||||||||||||||
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References
- [1]. Dawson WD, et al. Parallel changes in amino acid transport and protein kinase C localization in LLC-PK1 cells treated with TPA or diradylglycerols. J Cell Physiol. 1987 Jul;132(1):104-10. [Content Brief]
- [2]. Tang Y, et al. The Regulatory Role of MeAIB in Protein Metabolism and the mTOR Signaling Pathway in Porcine Enterocytes. Int J Mol Sci. 2018 Mar 2;19(3):714. [Content Brief]
