77222-61-8
Chemical Structure
BVDU 5′-Triphosphate
Synonym(s): (E)-5-(2-Bromovinyl)-dUTP; BVdUTP
- CAS No.: 77222-61-8
- Formula:C11H16BrN2O14P3
- Molecular Weight:573.08
IUPAC Name: (((2R,3S,5R)-5-(5-((E)-2-bromovinyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl)triphosphoric acid
InChIKey: BDKFDDMJXWAXHI-PIXDULNESA-N
SMILES: OP(OP(OP(O)(OC[C@@H]1[C@@H](O)C[C@H](N2C(NC(C(/C=C/Br)=C2)=O)=O)O1)=O)(O)=O)(O)=O
Biological Activity: BVDU 5′-Triphosphate is an antivirus agent with 5′-Triphosphate label, targeting viral DNA polymerase. BVDU 5′-Triphosphate shows excellent selectivity against varicella-zoster virus (VZV) and herpes simplex virus type 1 (HSV-1), due to a specific phosphorylation by the virus-encoded thymidine kinase.
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BVDU 5′-Triphosphate | BVDU 5′-Triphosphate is an antivirus agent with 5′-Triphosphate label, targeting viral DNA polymerase. BVDU 5′-Triphosphate shows excellent selectivity against varicella-zoster virus (VZV) and herpes simplex virus type 1 (HSV-1), due to a specific phosphorylation by the virus-encoded thymidine kinase. | |||||||||||||||||||||
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