77521-29-0
77521-29-0
Chemical Structure
(RS)-AMPA
Synonym(s): (±)-AMPA
- CAS No.: 77521-29-0
- Formula:C7H10N2O4
- Molecular Weight:186.17
IUPAC Name: 2-amino-3-(5-methyl-3-oxo-2,3-dihydroisoxazol-4-yl)propanoic acid
InChIKey: UUDAMDVQRQNNHZ-UHFFFAOYSA-N
SMILES: O=C1C(CC(N)C(O)=O)=C(C)ON1
Biological Activity: (RS)-AMPA ((±)-AMPA) is the racemate of AMPA. (RS)-AMPA is a glutamate analogue and a potent, selective agonist of the excitatory neurotransmitter L-glutamic acid. (RS)-AMPA does not interfere with the binding sites of kainate or NMDA receptors[1][2].
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(RS)-AMPA | 99.91% | (RS)-AMPA ((±)-AMPA) is the racemate of AMPA. (RS)-AMPA is a glutamate analogue and a potent, selective agonist of the excitatory neurotransmitter L-glutamic acid. (RS)-AMPA does not interfere with the binding sites of kainate or NMDA receptors. | ||||||||||||||||||||
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(RS)-AMPA (Standard) | ≥98% | (RS)-AMPA (Standard) ((±)-AMPA (Standard)) is the analytical standard of (RS)-AMPA (HY-100815B). This product is intended for research and analytical applications. (RS)-AMPA ((±)-AMPA) is the racemate of AMPA. (RS)-AMPA is a glutamate analogue and a potent, selective agonist of the excitatory neurotransmitter L-glutamic acid. (RS)-AMPA does not interfere with the binding sites of kainate or NMDA receptors. | ||||||||||||||||||||
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References
- [1]. Hösli L, et al. Effects of the glutamate analogue AMPA and its interaction with antagonists on cultured rat spinal and brain stem neurones. Neurosci Lett. 1983 Mar 28;36(1):59-62. [Content Brief]
- [2]. Sommer B, et al. Flip and flop: a cell-specific functional switch in glutamate-operated channels of the CNS. Science. 1990 Sep 28;249(4976):1580-5. [Content Brief]
