77591-18-5
77591-18-5
Chemical Structure
Tiopronin-cysteine disulfide
- CAS No.: 77591-18-5
- Formula:C8H14N2O5S2
- Molecular Weight:282.34
IUPAC Name: S-((1-((carboxymethyl)amino)-1-oxopropan-2-yl)thio)-L-cysteine
InChIKey: ABRJVLRUVDJIJJ-AKGZTFGVSA-N
SMILES: N[C@H](C(O)=O)CSSC(C(NCC(O)=O)=O)C
Biological Activity: Tiopronin-cysteine disulfide is a soluble disulfide metabolite/derivative of Tiopronin (HY-B0373) formed by reaction of Tiopronin with cystine. Tiopronin-cysteine disulfide reduces cystine crystal formation in cystinuria. Tiopronin-cysteine disulfide can be used for the research of cystinuria[1][2].
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Tiopronin-cysteine disulfide | 96.78% | Tiopronin-cysteine disulfide is a soluble disulfide metabolite/derivative of Tiopronin (HY-B0373) formed by reaction of Tiopronin with cystine. Tiopronin-cysteine disulfide reduces cystine crystal formation in cystinuria. Tiopronin-cysteine disulfide can be used for the research of cystinuria. | ||||||||||||||||||||
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References
- [1]. Lindell A, et al. Clinical course and cystine stone formation during tiopronin treatment. Urol Res. 1995;23(2):111-117. [Content Brief]
- [2]. Kumar A, et al. Chemical Modification of Tiopronin for Dual Management of Cystinuria and Associated Bacterial Infections. ACS Appl Mater Interfaces. 2023;15(37):43332-43344. [Content Brief]
