77769-21-2
77769-21-2
Chemical Structure
1,2-Dihydrotanshinone
Synonym(s): 1,2-Dihydrotanshinquinone
- CAS No.: 77769-21-2
- Formula:C18H14O3
- Molecular Weight:278.30
IUPAC Name: 1,6-dimethyl-8,9-dihydrophenanthro[1,2-b]furan-10,11-dione
InChIKey: OYOSADAKNZWZGA-UHFFFAOYSA-N
SMILES: O=C(C1=C2C=CC3=C1CCC=C3C)C(C4=C2OC=C4C)=O
Biological Activity: 1,2-Dihydrotanshinone (1,2-Dihydrotanshinquinone) is an abietane diterpene. 1,2-Dihydrotanshinone inhibits the formation of the pathogenic complex formed between (CUG)n-RNA and the splicing-factor muscleblind-like 1 (MBNL1). 1,2-Dihydrotanshinone can be used for the research of myotonic dystrophy type 1[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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1,2-Dihydrotanshinone | 99.75% | 1,2-Dihydrotanshinone (1,2-Dihydrotanshinquinone) is an abietane diterpene. 1,2-Dihydrotanshinone inhibits the formation of the pathogenic complex formed between (CUG)n-RNA and the splicing-factor muscleblind-like 1 (MBNL1). 1,2-Dihydrotanshinone can be used for the research of myotonic dystrophy type 1. | ||||||||||||||||||||
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References
- [1]. Faleschini MT, et, al. Discovery of natural products potentially active against myotonic dystrophy type 1. Planta Med 2015; 81-YRW_03.
- [2]. Fronza M, et, al. In vitro cytotoxic activity of abietane diterpenes from Peltodon longipes as well as Salvia miltiorrhiza and Salvia sahendica. Bioorg Med Chem. 2011 Aug 15;19(16):4876-81. [Content Brief]
