779356-64-8
779356-64-8
Chemical Structure
Denibulin hydrochloride
Synonym(s): MN-029
- CAS No.: 779356-64-8
- Formula:C18H20ClN5O3S
- Molecular Weight:421.90
IUPAC Name: methyl (S)-(5-((4-(2-aminopropanamido)phenyl)thio)-1H-benzo[d]imidazol-2-yl)carbamate hydrochloride
InChIKey: JUMSCXLBFWHCRA-PPHPATTJSA-N
SMILES: O=C(OC)NC1=NC2=CC(SC3=CC=C(NC([C@@H](N)C)=O)C=C3)=CC=C2N1.Cl
Biological Activity: Denibulin (MN-029) hydrochloride is an anti-angiogenic agent with anticancer activity. It can cause rapid closure of blood vessels in solid tumors and lead to dose-dependent killing of tumor cells, effectively enhancing the antitumor effects of radiation and cisplatin chemotherapy[1].
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Denibulin hydrochloride | Denibulin (MN-029) hydrochloride is an anti-angiogenic agent with anticancer activity. It can cause rapid closure of blood vessels in solid tumors and lead to dose-dependent killing of tumor cells, effectively enhancing the antitumor effects of radiation and cisplatin chemotherapy. | |||||||||||||||||||||
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