78263-91-9
78263-91-9
Chemical Structure
2-Methyl-5-HT maleate
Synonym(s): 2-Methyl-5-hydroxytryptamine maleate; 2-Methylserotonin maleate; 2-Me-HT maleate
- CAS No.: 78263-91-9
- Formula:C15H18N2O5
- Molecular Weight:306.31
IUPAC Name: 3-(2-aminoethyl)-2-methyl-1H-indol-5-ol maleate
InChIKey: KFEAUMZKRNJEDU-BTJKTKAUSA-N
SMILES: O=C(O)/C=C\C(O)=O.OC1=CC2=C(NC(C)=C2CCN)C=C1
Biological Activity: 2-Methyl-5-HT maleate (2-Methyl-5-hydroxytryptamine maleate) is a potent and selective 5-HT3 receptor agonist. 2-Methyl-5-HT maleate is shown to display anti-depressive-like effects[1].
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2-Methyl-5-HT maleate | 2-Methyl-5-HT maleate (2-Methyl-5-hydroxytryptamine maleate) is a potent and selective 5-HT3 receptor agonist. 2-Methyl-5-HT maleate is shown to display anti-depressive-like effects. | |||||||||||||||||||||
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References
- [1]. Sumaya IC, et al. Differential effects of a short-term high-fat diet in an animal model of depression in rats treated with the 5-HT3 receptor antagonist, ondansetron, the 5-HT3 receptor agonist, 2-methyl-5-HT, and the SSRI, fluoxetine. Pharmacol Biochem Behav. 2016 May;144:78-84. [Content Brief]
