791595-09-0
791595-09-0
Chemical Structure
DMAPT
Synonym(s): Dimethylamino Parthenolide
- CAS No.: 791595-09-0
- Formula:C17H27NO3
- Molecular Weight:293.40
IUPAC Name: (1aR,7aS,8R,10aS,10bR,Z)-8-((dimethylamino)methyl)-1a,5-dimethyl-2,3,6,7,7a,8,10a,10b-octahydrooxireno[2',3':9,10]cyclodeca[1,2-b]furan-9(1aH)-one
InChIKey: UJNSFDHVIBGEJZ-WCOQXKCFSA-N
SMILES: C[C@]12[C@@](O2)([H])[C@]3([H])[C@](CC/C(C)=C\CC1)([H])[C@@H](C(O3)=O)CN(C)C
Biological Activity: DMAPT (Dimethylamino Parthenolide), an analogue of Parthenolide (PTL), is an oral active NF-κB inhibitor, with a LD50 of 1.7 μM for cell population in AML cells. Has potential anti-cancer and anti-metastatic effect[1].
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DMAPT | 98.95% | DMAPT (Dimethylamino Parthenolide), an analogue of Parthenolide (PTL), is an oral active NF-κB inhibitor, with a LD50 of 1.7 μM for cell population in AML cells. Has potential anti-cancer and anti-metastatic effect. | ||||||||||||||||||||
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