793671-47-3

8-Chloro-ATP tetrasodium Chemical Structure
793671-47-3

Chemical Structure

8-Chloro-ATP tetrasodium

  • CAS No.: 793671-47-3
  • Formula:C10H11ClN5Na4O13P3
  • Molecular Weight:629.55

IUPAC Name: sodium ((2R,3S,4R,5R)-5-(6-amino-8-chloro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl triphosphate

InChIKey: BIFUJGGPLKGBNZ-ZVQJTLEUSA-J

SMILES: NC1=NC=NC2=C1N=C(Cl)N2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(OP(OP(O[Na])(O[Na])=O)(O[Na])=O)(O[Na])=O)O3

Biological Activity: 8-Chloro-ATP tetrasodium, an ATP (HY-B2176) analog, is a topoisomerase II (Topo II) inhibitor. 8-Chloro-ATP tetrasodium inhibits DNA synthesis and induces DNA double-stranded breaks (DSBs). 8-Chloro-ATP tetrasodium inhibits Topo II-catalyzed ATP hydrolysis[1].

Cat. No. Product Name Purity Description Pricing
HY-134290A
8-Chloro-ATP tetrasodium 8-Chloro-ATP tetrasodium, an ATP (HY-B2176) analog, is a topoisomerase II (Topo II) inhibitor. 8-Chloro-ATP tetrasodium inhibits DNA synthesis and induces DNA double-stranded breaks (DSBs). 8-Chloro-ATP tetrasodium inhibits Topo II-catalyzed ATP hydrolysis.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References