79404-98-1
79404-98-1
Chemical Structure
Demethylmacrocin
- CAS No.: 79404-98-1
- Formula:C44H73NO17
- Molecular Weight:888.05
InChIKey: ALZAOGATQMXJKX-ZTKVJMLBSA-N
SMILES: O=CCC1CC(C)C(/C=C\C(C)=C\C(C(CC)OC(CC(C(C1OC2OC(C(C(C2O)N(C)C)OC3OC(C(C(C)(C3)O)O)C)C)C)O)=O)COC4OC(C(C(C4O)O)O)C)=O
Biological Activity: Demethylmacrocin is a key intermediate in the biosynthetic pathway of Tylosin (HY-B0519A). Demethylmacrocin can be efficiently converted into tylosin through specific sequential oxidation and methylation reactions[1][2].
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Demethylmacrocin | Demethylmacrocin is a key intermediate in the biosynthetic pathway of Tylosin (HY-B0519A). Demethylmacrocin can be efficiently converted into tylosin through specific sequential oxidation and methylation reactions. | |||||||||||||||||||||
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References
- [1]. Kim E, et al. Characterization of the Two Methylation Steps Involved in the Biosynthesis of Mycinose in Tylosin. J Nat Prod. 2016 Aug 26;79(8):2014-21. [Content Brief]
- [2]. Baltz RH, et al. Biosynthesis of the macrolide antibiotic tylosin. A preferred pathway from tylactone to tylosin. J Antibiot (Tokyo). 1983 Feb;36(2):131-41. [Content Brief]
