794510-70-6
794510-70-6
Chemical Structure
ETP-45835
- CAS No.: 794510-70-6
- Formula:C13H16N4
- Molecular Weight:228.29
InChIKey: VXNHTGWDWVCFSI-UHFFFAOYSA-N
SMILES: N=1C=CC(=CC1)C2=NNC(=C2)C3CCNCC3
Biological Activity: ETP-45835 is slective and potent MNK inhibitor with IC50s of 575 nM and 646 nM for MNK1 and MNK2, respectively. ETP-45835 shows little activity against 24 other kinases. ETP-45835 inhibits eIF4E Ser209 phosphorylation in cells, and has anticancer effects[1].
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ETP-45835 | ETP-45835 is slective and potent MNK inhibitor with IC50s of 575 nM and 646 nM for MNK1 and MNK2, respectively. ETP-45835 shows little activity against 24 other kinases. ETP-45835 inhibits eIF4E Ser209 phosphorylation in cells, and has anticancer effects. | |||||||||||||||||||||
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