798543-50-7
798543-50-7
Chemical Structure
KBH-A42
- CAS No.: 798543-50-7
- Formula:C17H22N2O3
- Molecular Weight:302.37
IUPAC Name: N-hydroxy-3-(2-oxo-1-(3-phenylpropyl)-1,2,5,6-tetrahydropyridin-3-yl)propanamide
InChIKey: QVZVOPUKMAJJHD-UHFFFAOYSA-N
SMILES: O=C(CCC1=CCCN(C1=O)CCCC2=CC=CC=C2)NO
Biological Activity: KBH-A42 is a novel histone deacetylase (HDAC) inhibitor with significant anti-inflammatory properties. KBH-A42 against TNF-α and NO production with IC50 values of 1.10 and 2.71 µM, respectively, in the LPS-induced murine macrophage RAW 264.7 cells[1].
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KBH-A42 | KBH-A42 is a novel histone deacetylase (HDAC) inhibitor with significant anti-inflammatory properties. KBH-A42 against TNF-α and NO production with IC50 values of 1.10 and 2.71 µM, respectively, in the LPS-induced murine macrophage RAW 264.7 cells. | |||||||||||||||||||||
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