80651-95-2
80651-95-2
Chemical Structure
Suc-Ala-Ala-Pro-Phe-SBzl
- CAS No.: 80651-95-2
- Formula:C31H38N4O7S
- Molecular Weight:610.72
InChIKey: TWURVFFNODFJBJ-NBMBROAQSA-N
SMILES: OC(CCC(N[C@@H](C)C(N[C@@H](C)C(N1[C@@H](CCC1)C(N[C@H](C(SCC2=CC=CC=C2)=O)CC3=CC=CC=C3)=O)=O)=O)=O)=O
Biological Activity: Suc-Ala-Ala-Pro-Phe-SBzl can be used as the substrate of rat intestinal mast cell protease (RMCP I), rat skeletal muscle mast cell protease (RMCP II) and Chymotrypsin (HY-108910). Suc-Ala-Ala-Pro-Phe-SBzl can be hydrolyzed by glycine (R208G)[1][2].
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Suc-Ala-Ala-Pro-Phe-SBzl | Suc-Ala-Ala-Pro-Phe-SBzl can be used as the substrate of rat intestinal mast cell protease (RMCP I), rat skeletal muscle mast cell protease (RMCP II) and Chymotrypsin (HY-108910). Suc-Ala-Ala-Pro-Phe-SBzl can be hydrolyzed by glycine (R208G). | |||||||||||||||||||||
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References
- [1]. Harper JW, et al. Reaction of peptide thiobenzyl esters with mammalian chymotrypsinlike enzymes: a sensitive assay method. Anal Biochem. 1981 Dec;118(2):382-7. [Content Brief]
- [2]. Caputo A, et al. Conversion of the substrate specificity of mouse proteinase granzyme B. Nat Struct Biol. 1994 Jun;1(6):364-7. [Content Brief]
