80734-02-7
Chemical Structure
Lenampicillin hydrochloride
Synonym(s): KBT 1585 hydrochloride
- CAS No.: 80734-02-7
- Formula:C21H24ClN3O7S
- Molecular Weight:497.95
IUPAC Name: (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl (2S,5R,6R)-6-((R)-2-amino-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate hydrochloride
InChIKey: FXXSETTYJSGMCR-GLCLSGQWSA-N
SMILES: O=C([C@@H]1N(C2=O)[C@]([C@@H]2NC([C@@H](C3=CC=CC=C3)N)=O)([H])SC1(C)C)OCC(OC4=O)=C(O4)C.Cl
Biological Activity: Lenampicillin hydrochloride (KBT 1585 hydrochloride) is an orally active proagent of Ampicillin and is an effective beta-lactam antibacterial agent that inhibits bacterial penicillin-binding proteins (transpeptidase). Lenampicillin hydrochloride has improved absorption and decreased side effects compares to Ampicillin and is applied in the investigation of the suppurative skin and soft tissue infection [1] [2] [3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Lenampicillin hydrochloride | 98.96% | Lenampicillin hydrochloride (KBT 1585 hydrochloride) is an orally active proagent of Ampicillin and is an effective beta-lactam antibacterial agent that inhibits bacterial penicillin-binding proteins (transpeptidase). Lenampicillin hydrochloride has improved absorption and decreased side effects compares to Ampicillin and is applied in the investigation of the suppurative skin and soft tissue infection . | ||||||||||||||||||||
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References
- [1]. FUMIO OGINO, et al. ACUTE TOXICITY OF LENAMPICILLIN HYDROCHLORIDE (KBT-1585) IN MICE, RATS AND DOGS
- [2]. Yamabe S, et al. Non-mutagenicity of KBT-1585, a novel ester of ampicillin.Chemioterapia. 1984 Feb;3(1):60-2. [Content Brief]
- [3]. Fujita K, et al. Clinical evaluation of lenampicillin in the treatment of superficial suppurative skin and soft tissue infection. A double-blind study comparing amoxicillin.Jpn J Antibiot. 1985 Jul;38(7):1794-818. [Content Brief]
