80755-87-9
80755-87-9
Chemical Structure
Lys-Gln-Ala-Gly-Asp-Val
- CAS No.: 80755-87-9
- Formula:C25H44N8O10
- Molecular Weight:616.66
InChIKey: AFAFFVKJJYBBTC-YPTDYUDTSA-N
SMILES: CC(C)[C@@H](C(O)=O)NC([C@H](CC(O)=O)NC(CNC([C@H](C)NC([C@H](CCC(N)=O)NC([C@@H](N)CCCCN)=O)=O)=O)=O)=O
Biological Activity: Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) is the six most carboxyl-terminal amino acids in the fibrinogen γ-chain sequence. Lys-Gln-Ala-Gly-Asp-Val is a cell adhesion peptide which is mediated through the α2bβ3 integrin. Lys-Gln-Ala-Gly-Asp-Val is a potent adhesion ligand for smooth muscle cells (SMCs)[1][2].
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Lys-Gln-Ala-Gly-Asp-Val | 99.50% | Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) is the six most carboxyl-terminal amino acids in the fibrinogen γ-chain sequence. Lys-Gln-Ala-Gly-Asp-Val is a cell adhesion peptide which is mediated through the α2bβ3 integrin. Lys-Gln-Ala-Gly-Asp-Val is a potent adhesion ligand for smooth muscle cells (SMCs). | ||||||||||||||||||||
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References
- [1]. Dong CL, et al. The cytocompatability of polyhydroxyalkanoates coated with a fusion protein of PHA repressor protein (PhaR) and Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) polypeptide. Biomaterials. 2012 Mar;33(9):2593-9. [Content Brief]
- [2]. Mann BK, et al. Tethered-TGF-beta increases extracellular matrix production of vascular smooth muscle cells. Biomaterials. 2001 Mar;22(5):439-44. [Content Brief]
