81117-35-3
Chemical Structure
N-Nonyldeoxynojirimycin
Synonym(s): NN-DNJ; Nonyl-DNJ
- CAS No.: 81117-35-3
- Formula:C15H31NO4
- Molecular Weight:289.41
IUPAC Name: (2R,3R,4R,5S)-2-(hydroxymethyl)-1-nonylpiperidine-3,4,5-triol
InChIKey: FTSCEGKYKXESFF-LXTVHRRPSA-N
SMILES: OC[C@H]1N(C[C@H](O)[C@@H](O)[C@@H]1O)CCCCCCCCC
Biological Activity: N-Nonyldeoxynojirimycin (NN-DNJ) is a deoxynojirimycin derivative with a hydrophobic long chain. N-Nonyldeoxynojirimycin is an orally active inhibitor of acid α-glucosidase (IC50: 0.42 μM) and α-1,6-glucosidase (IC50: 8.4 μM). N-Nonyldeoxynojirimycin has activities of inhibiting glycogen breakdown, anti-virus and anti-tumor. N-Nonyldeoxynojirimycin also has insecticidal effects, with an LD50 of 5 mM for adults of Bemisia tabaci[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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N-Nonyldeoxynojirimycin | 98.0% | N-Nonyldeoxynojirimycin (NN-DNJ) is a deoxynojirimycin derivative with a hydrophobic long chain. N-Nonyldeoxynojirimycin is an orally active inhibitor of acid α-glucosidase (IC50: 0.42 μM) and α-1,6-glucosidase (IC50: 8.4 μM). N-Nonyldeoxynojirimycin has activities of inhibiting glycogen breakdown, anti-virus and anti-tumor. N-Nonyldeoxynojirimycin also has insecticidal effects, with an LD50 of 5 mM for adults of Bemisia tabaci. | ||||||||||||||||||||
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N-Nonyldeoxynojirimycin (Standard) | ≥98% | N-Nonyldeoxynojirimycin (Standard) is the analytical standard of N-Nonyldeoxynojirimycin (HY-107532). This product is intended for research and analytical applications. N-Nonyldeoxynojirimycin (NN-DNJ) is a deoxynojirimycin derivative with a hydrophobic long chain. N-Nonyldeoxynojirimycin is an orally active inhibitor of acid α-glucosidase (IC50: 0.42 μM) and α-1,6-glucosidase (IC50: 8.4 μM). N-Nonyldeoxynojirimycin has activities of inhibiting glycogen breaKdown, anti-virus and anti-tumor. N-Nonyldeoxynojirimycin also has insecticidal effects, with an LD50 of 5 mM for adults of Bemisia tabaci. | ||||||||||||||||||||
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References
- [1]. Zitzmann N, et al. Imino sugars inhibit the formation and secretion of bovine viral diarrhea virus, a pestivirus model of hepatitis C virus: implications for the development of broad spectrum anti-hepatitis virus agents. Proc Natl Acad Sci U S A. 1999 Oct 12;96(21):11878-82. [Content Brief]
- [2]. Andersson U, et al. Inhibition of glycogen breakdown by imino sugars in vitro and in vivo. Biochem Pharmacol. 2004 Feb 15;67(4):697-705. [Content Brief]
- [3]. Ranes M K. Influence of imino sugars on the growth and ganglioside content of two experimental mouse brain tumors. Boston College, 2000.
- [4]. Ya'kobovitz MK, et al. Inhibition of α-glucosidase activity by N-deoxynojirimycin analogs in several insect phloem sap feeders. Insect Sci. 2016 Feb;23(1):59-67. [Content Brief]
