819058-88-3
819058-88-3
Chemical Structure
A-849529
- CAS No.: 819058-88-3
- Formula:C21H16FN5O3
- Molecular Weight:405.38
SMILES: O=C(C1=CC=C(C(NC(NC2=CC=C(C3=C4C(N)=NNC4=CC=C3)C=C2)=O)=C1)F)O
Biological Activity: A-849529 is an acid metabolite of ABT-869 (HY-50751). ABT-869 is a potent and orally active multi-target inhibitor of VEGFR and PDGFR family[1].
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A-849529 | A-849529 is an acid metabolite of ABT-869 (HY-50751). ABT-869 is a potent and orally active multi-target inhibitor of VEGFR and PDGFR family. | |||||||||||||||||||||
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References
- [1]. Rodila rc, et, al. A high-throughput, fully automated liquid/liquid extraction liquid chromatography/mass spectrometry method for the quantitation of a new investigational drug ABT-869 and its metabolite A-849529 in human plasma samples. Rapid Commun Mass Spectrom. 2006;20(20):3067-75. [Content Brief]
