819827-50-4
819827-50-4
Chemical Structure
CB7993113
- CAS No.: 819827-50-4
- Formula:C15H10BrNO5
- Molecular Weight:364.15
IUPAC Name: 2-((2-(5-bromofuran-2-yl)-4-oxo-4H-chromen-3-yl)oxy)acetamide
InChIKey: KGIGMCONNWRUGX-UHFFFAOYSA-N
SMILES: O=C(N)COC1=C(C2=CC=C(Br)O2)OC3=CC=CC=C3C1=O
Biological Activity: CB7993113 is a potent AHR antagonist, with an IC50 of 0.33 μM. CB7993113 directly binds AHR protein and blocks AHR nuclear translocation. CB7993113 inhibits polycyclic aromatic hydrocarbon (PAH)- and TCDD-induced reporter activity by 75% and 90% respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
CB7993113 | 98.0% | CB7993113 is a potent AHR antagonist, with an IC50 of 0.33 μM. CB7993113 directly binds AHR protein and blocks AHR nuclear translocation. CB7993113 inhibits polycyclic aromatic hydrocarbon (PAH)- and TCDD-induced reporter activity by 75% and 90% respectively. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
CB7993113 (Standard) | ≥98% | CB7993113 (Standard) is the analytical standard of CB7993113 (HY-111450). This product is intended for research and analytical applications. CB7993113 is a potent AHR antagonist, with an IC50 of 0.33 μM. CB7993113 directly binds AHR protein and blocks AHR nuclear translocation. CB7993113 inhibits polycyclic aromatic hydrocarbon (PAH)- and TCDD-induced reporter activity by 75% and 90% respectively. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
