82-57-5
82-57-5
Chemical Structure
Visnagin
- CAS No.: 82-57-5
- Formula:C13H10O4
- Molecular Weight:230.22
IUPAC Name: 4-methoxy-7-methyl-5H-furo[3,2-g]chromen-5-one
InChIKey: NZVQLVGOZRELTG-UHFFFAOYSA-N
SMILES: O=C1C=C(C)OC2=CC(OC=C3)=C3C(OC)=C12
Biological Activity: Visnagin, an antioxidant furanocoumarin derivative, possess anti-inflammatory and analgesic properties. Visnagin has substantial potential to prevent Cerulein induced acute pancreatitis (AP). Visnagin possess promising vasodilator effects in vascular smooth muscles[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Visnagin | 99.34% | Visnagin, an antioxidant furanocoumarin derivative, possess anti-inflammatory and analgesic properties. Visnagin has substantial potential to prevent Cerulein induced acute pancreatitis (AP). Visnagin possess promising vasodilator effects in vascular smooth muscles. | ||||||||||||||||||||
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Visnagin (Standard) | ≥98% | Visnagin, an antioxidant furanocoumarin derivative, possess anti-inflammatory and analgesic properties. Visnagin has substantial potential to prevent Cerulein induced acute pancreatitis (AP). Visnagin possess promising vasodilator effects in vascular smooth muscles. | ||||||||||||||||||||
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Khellinol | Khellinol (5-Norkhellin) is a nature product that can be found in Ammi visnaga fruits. | |||||||||||||||||||||
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Rubrofusarin | 98.19% | Rubrofusarin is an orange polyketide pigment from Fusarium graminearum. Rubrofusarin is also an active ingredient of the Cassia species and ameliorates chronic restraint stress (CRS) -induced depressive symptoms through PI3K/Akt signaling. Rubrofusarin has anticancer, antibacterial, and antioxidant effects. | ||||||||||||||||||||
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Khellin | 99.66% | Khellin is a furochromone that can be isolated from Ammi visnuga L.. Khellin is an EGFR inhibitor with an IC50 of 0.15 µM. Khelline has anti-proliferative activity in vitro. Khellin has antispasmodic and coronary vasodilator effects. | ||||||||||||||||||||
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Bergapten (Standard) | ≥98% | Bergapten (Standard) is the analytical standard of Bergapten. This product is intended for research and analytical applications. Bergapten is a natural anti-inflammatory and anti-tumor agent. Bergapten is inhibitory towards mouse and human CYP isoforms. | ||||||||||||||||||||
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Isobergapten (Standard) | ≥98% | Isobergapten (Standard) is the analytical standard of Isobergapten. This product is intended for research and analytical applications. Isobergapten is an allelopathic inhibitor isolated from seeds of Hevacleum laciniatum. | ||||||||||||||||||||
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Norrubrofusarin | 99.64% | Norrubrofusarin (Didemethylasperxanthone) is a natural product that can be obtained by demethylation of the metabolite (Compound III) of Aspergillus nige. | ||||||||||||||||||||
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Khellol | Khellol is a furanochromone derivative with feeding deterrent activity against insects. Khellol induces 12.12 % feeding inhibition at 100 ppm against Spodoptma litura larvae. | |||||||||||||||||||||
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Demethylvisnagin | Demethylvisnagin is a furanochromone derivative with extremely weak spasmolytic activity. | |||||||||||||||||||||
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Norkhellol | Norkhellol is a Flavonoids product that can be isolated from the roots of Cimicifuga foetida. | |||||||||||||||||||||
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Eugenitin | Eugenitin is a polyketide isolated from the fungus Mycoleptodiscus indicus that is related to the South American medicinal plant. Eugenitin inhibits Leishmania major with LD50=39.9 μM. Eugenitin has low cytotoxicity (IC50 >131 μM) against several human cancer cell lines. | |||||||||||||||||||||
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References
- [1]. Radim Vrzal, et al. Khellin and visnagin differentially modulate AHR signaling and downstream CYP1A activity in human liver cells. PLoS One. 2013 Sep 19;8(9):e74917. [Content Brief]
- [2]. Lakshmi Priya Pasari, et al. Visnagin attenuates acute pancreatitis via Nrf2/NFκB pathway and abrogates associated multiple organ dysfunction. Biomed Pharmacother. 2019 Apr;112:108629. [Content Brief]
