82381-67-7
82381-67-7
Chemical Structure
Ro 31-0052
- CAS No.: 82381-67-7
- Formula:C11H18N4O4
- Molecular Weight:270.29
IUPAC Name: 1-(2-hydroxy-3-(2-nitro-1H-imidazol-1-yl)propyl)piperidin-3-ol
InChIKey: NZLBVURLEKAMKZ-UHFFFAOYSA-N
SMILES: OC(CN1CC(CCC1)O)CN2C=CN=C2[N+]([O-])=O
Biological Activity: Ro 31-0052 is a basic radiation sensitizer, a 3'-hydroxypiperidine analog of Ro 03-8799, with improved hydrophilicity. This type of designed radiation sensitizer has better pharmacokinetic properties and has the potential to replace clinically used Misonidazole (HY-105061) and Metronidazole (HY-B0318)[1].
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Ro 31-0052 | Ro 31-0052 is a basic radiation sensitizer, a 3'-hydroxypiperidine analog of Ro 03-8799, with improved hydrophilicity. This type of designed radiation sensitizer has better pharmacokinetic properties and has the potential to replace clinically used Misonidazole (HY-105061) and Metronidazole (HY-B0318). | |||||||||||||||||||||
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