827306-88-7
Chemical Structure
Acetyl tetrapeptide-3
- CAS No.: 827306-88-7
- Formula:C22H39N9O5
- Molecular Weight:509.60
IUPAC Name: (S)-2-acetamido-6-amino-N-(2-(((S)-1-(((S)-1,6-diamino-1-oxohexan-2-yl)amino)-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl)amino)-2-oxoethyl)hexanamide
InChIKey: RRJOMESUBQAYOA-BZSNNMDCSA-N
SMILES: NCCCC[C@@H](C(N)=O)NC([C@@H](NC(CNC([C@@H](NC(C)=O)CCCCN)=O)=O)CC1=CN=CN1)=O
Biological Activity: Acetyl tetrapeptide-3 is a synthetic peptide. Acetyl tetrapeptide-3 enhances the adhesion of hair follicles to the scalp but also promotes the development of new hair follicles. Acetyl tetrapeptide-3 stimulates the synthesis of collagen III in hair follicles. Acetyl tetrapeptide-3 combined with Biochanin A (HY-14595) and ginseng extracts, can stimulate dermal papilla extracellular matrix (ECM) proteins by increasing hydroxyproline, Collagen Type 3, and laminin, yielding a significant improvement in hair follicle size and hair anchoring[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Acetyl tetrapeptide-3 | 99.27% | Acetyl tetrapeptide-3 is a synthetic peptide. Acetyl tetrapeptide-3 enhances the adhesion of hair follicles to the scalp but also promotes the development of new hair follicles. Acetyl tetrapeptide-3 stimulates the synthesis of collagen III in hair follicles. Acetyl tetrapeptide-3 combined with Biochanin A (HY-14595) and ginseng extracts, can stimulate dermal papilla extracellular matrix (ECM) proteins by increasing hydroxyproline, Collagen Type 3, and laminin, yielding a significant improvement in hair follicle size and hair anchoring. | ||||||||||||||||||||
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References
- [1]. Suparuj Lueangarun, et al. An Herbal Extract Combination (Biochanin A, Acetyl tetrapeptide-3, and Ginseng Extracts) versus 3% Minoxidil Solution for the Treatment of Androgenetic Alopecia: A 24-week, Prospective, Randomized, Triple-blind, Controlled Trial. J Clin Aesthet Dermatol. 2020 Oct;13(10):32-37. [Content Brief]
- [2]. Bui Thi Phuong Hai, et al., (2025). TOTAL SYNTHESIS OF THE ACTIVE INGREDIENT ACETYL TETRAPEPTIDE-3 FOR HAIR LOSS TREATMENT AND SCALP CARE. Natural sciences 70(1).
- [3]. Li-Wei Tian, et al., Co-delivery of bioactive peptides by nanoliposomes for promotion of hair growth, Journal of Drug Delivery Science and Technology, Volume 72, 2022, 103381, ISSN 1773-2247.
