827318-97-8
827318-97-8
Chemical Structure
Danusertib
Synonym(s): PHA-739358
- CAS No.: 827318-97-8
- Formula:C26H30N6O3
- Molecular Weight:474.55
IUPAC Name: (R)-N-(5-(2-methoxy-2-phenylacetyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)-4-(4-methylpiperazin-1-yl)benzamide
InChIKey: XKFTZKGMDDZMJI-HSZRJFAPSA-N
SMILES: O=C(N1CC2=C(NN=C2NC(C3=CC=C(N4CCN(CC4)C)C=C3)=O)C1)[C@@H](C5=CC=CC=C5)OC
Biological Activity: Danusertib is a pyrrolo-pyrazole and aurora kinase inhibitor with IC50 of 13, 79, and 61 nM for Aurora A, B, and C, respectively.
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Danusertib | 99.68% | Danusertib is a pyrrolo-pyrazole and aurora kinase inhibitor with IC50 of 13, 79, and 61 nM for Aurora A, B, and C, respectively. | ||||||||||||||||||||
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Danusertib (Standard) | ≥98% | Danusertib (Standard) is the analytical standard of Danusertib. This product is intended for research and analytical applications. Danusertib is a pyrrolo-pyrazole and aurora kinase inhibitor with IC50 of 13, 79, and 61 nM for Aurora A, B, and C, respectively. | ||||||||||||||||||||
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