827319-43-7
Chemical Structure
GW-870086
- CAS No.: 827319-43-7
- Formula:C31H39F2NO6
- Molecular Weight:559.64
IUPAC Name: cyanomethyl (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-((2,2,3,3-tetramethylcyclopropane-1-carbonyl)oxy)-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylate
InChIKey: WUBKGTSFJSEIEM-NSHBDUGJSA-N
SMILES: O=C(C1C(C)(C)C1(C)C)O[C@]2([C@@]3([C@@]([C@@]4([H])[C@@](F)([C@@]5(C([C@@H](F)C4)=CC(C=C5)=O)C)[C@@H](O)C3)([H])C[C@H]2C)C)C(OCC#N)=O
Biological Activity: GW-870086 is a potent anti-inflammatory agent, acting as a glucocorticoid receptor agonist, with a pIC50 of 10.1 in A549 cells expressing NF-κB.
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GW-870086 | 99.59% | GW-870086 is a potent anti-inflammatory agent, acting as a glucocorticoid receptor agonist, with a pIC50 of 10.1 in A549 cells expressing NF-κB. | ||||||||||||||||||||
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GW-870086 (Standard) | ≥98% | GW-870086 (Standard) is the analytical standard of GW-870086 (HY-103662). This product is intended for research and analytical applications. GW-870086 is a potent anti-inflammatory agent, acting as a glucocorticoid receptor agonist, with a pIC50 of 10.1 in A549 cells expressing NF-κB. | ||||||||||||||||||||
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