82958-11-0
Chemical Structure
AF 698
- CAS No.: 82958-11-0
- Formula:C28H26N2O4
- Molecular Weight:454.52
IUPAC Name: 3-oxo-1,3-dihydroisobenzofuran-1-yl (41S,13aS)-13a-ethyl-2,3,41,5,6,13a-hexahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylate
InChIKey: PEZLCFUBKMKIJA-NMZBPYGDSA-N
SMILES: O=C(OC1OC(C2=CC=CC=C21)=O)C3=C[C@@](CCC4)(CC)[C@@](N4CC5)([H])C6=C5C7=CC=CC=C7N36
Biological Activity: AF 698 is a phthalate derivative of Apovincamine (HY-135743) that can be used as a peripheral vasodilator with selective vasomotor effects on cerebral microvascular circulation. AF 698 has better vasodilator effect than Vincamine (HY-B1021), but there is no significant difference in the protective effect of the two drugs against hypobaric hypoxia-induced lethality in mice[1].
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AF 698 | AF 698 is a phthalate derivative of Apovincamine (HY-135743) that can be used as a peripheral vasodilator with selective vasomotor effects on cerebral microvascular circulation. AF 698 has better vasodilator effect than Vincamine (HY-B1021), but there is no significant difference in the protective effect of the two drugs against hypobaric hypoxia-induced lethality in mice. | |||||||||||||||||||||
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