83707-15-7
83707-15-7
Chemical Structure
MANT-cGMP
- CAS No.: 83707-15-7
- Formula:C18H19N6O8P
- Molecular Weight:478.35
IUPAC Name: (4aR,6R,7R,7aR)-6-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-2-hydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-yl 2-(methylamino)benzoate
InChIKey: WKGUYUNJVBVOOQ-XNIJJKJLSA-N
SMILES: O=C(C(C=CC=C1)=C1NC)O[C@H]2[C@@](N3C(NC(N)=NC4=O)=C4N=C3)([H])O[C@@](CO5)([H])[C@@]2([H])O[P]5(O)=O
Biological Activity: MANT-cGMP, a ribose-substituted nucleotide, is an adenylyl cyclase (AC) inhibitor with a Ki of 100 μM and a pKi of 4. MANT-cGMP can be used for the study of heart failure, cancer, and neurological disorders[1].
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MANT-cGMP | MANT-cGMP, a ribose-substituted nucleotide, is an adenylyl cyclase (AC) inhibitor with a Ki of 100 μM and a pKi of 4. MANT-cGMP can be used for the study of heart failure, cancer, and neurological disorders. | |||||||||||||||||||||
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