83861-29-4
Chemical Structure
GYKI-14451 sulfate
- CAS No.: 83861-29-4
- Formula:C25H39N6O7S0.5
- Molecular Weight:551.65
IUPAC Name: tert-butyl ((R)-1-((S)-2-(((S)-5-guanidino-1-oxopentan-2-yl)carbamoyl)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)carbamate sulfate
InChIKey: JSYTZZNMZGXXJY-NJBQKBHSSA-N
SMILES: O=S(O)(O)=O.CC(C)(C)OC(N[C@H](CC1=CC=CC=C1)C(N2[C@@H](CCC2)C(N[C@H](C=O)CCCNC(N)=N)=O)=O)=O
Biological Activity: GYKI-14451 sulfate is an inhibitor of thrombin and plasmin. GYKI-14451 sulfate inhibits thrombin-fibrinogen and plasmin-fibrin reactions. GYKI-14451 sulfate inhibits fibrin clot lysis and prolongs fibrin clot lysis time in a dose-dependent manner. GYKI-14451 sulfate does not undergo N-terminal cyclization and spontaneous inactivation in neutral aqueous buffer. GYKI-14451 sulfate can be used in studies related to venous thrombosis and fibrinogen solidification[1].
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GYKI-14451 sulfate | GYKI-14451 sulfate is an inhibitor of thrombin and plasmin. GYKI-14451 sulfate inhibits thrombin-fibrinogen and plasmin-fibrin reactions. GYKI-14451 sulfate inhibits fibrin clot lysis and prolongs fibrin clot lysis time in a dose-dependent manner. GYKI-14451 sulfate does not undergo N-terminal cyclization and spontaneous inactivation in neutral aqueous buffer. GYKI-14451 sulfate can be used in studies related to venous thrombosis and fibrinogen solidification. | |||||||||||||||||||||
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