839713-36-9
839713-36-9
Chemical Structure
Nelotanserin
Synonym(s): APD125
- CAS No.: 839713-36-9
- Formula:C18H15BrF2N4O2
- Molecular Weight:437.24
IUPAC Name: 1-(3-(4-bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl)-3-(2,4-difluorophenyl)urea
InChIKey: COSPVUFTLGQDQL-UHFFFAOYSA-N
SMILES: COC1=C(C2=C(Br)C=NN2C)C=C(NC(NC3=C(F)C=C(F)C=C3)=O)C=C1
Biological Activity: Nelotanserin is a potent 5-HT2A inverse agonist, a moderately potent 5-HT2C partial inverse agonist and a weak 5-HT2B inverse agonist, with IC50s of 1.7, 79, 791 nM in IP accumulation assays, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Nelotanserin | 99.66% | Nelotanserin is a potent 5-HT2A inverse agonist, a moderately potent 5-HT2C partial inverse agonist and a weak 5-HT2B inverse agonist, with IC50s of 1.7, 79, 791 nM in IP accumulation assays, respectively. | ||||||||||||||||||||
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Nelotanserin (Standard) | ≥98% | Nelotanserin (Standard) is the analytical standard of Nelotanserin (HY-10559). This product is intended for research and analytical applications. Nelotanserin is a potent 5-HT2A inverse agonist, a moderately potent 5-HT2C partial inverse agonist and a weak 5-HT2B inverse agonist, with IC50s of 1.7, 79, 791 nM in IP accumulation assays, respectively. | ||||||||||||||||||||
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