845614-12-2
Chemical Structure
Bitopertin (R enantiomer)
Synonym(s): RG1678 (R enantiomer); RO4917838 (R enantiomer)
- CAS No.: 845614-12-2
- Formula:C21H20F7N3O4S
- Molecular Weight:543.46
IUPAC Name: (R)-(4-(3-fluoro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)(5-(methylsulfonyl)-2-((1,1,1-trifluoropropan-2-yl)oxy)phenyl)methanone
InChIKey: YUUGYIUSCYNSQR-GFCCVEGCSA-N
SMILES: FC1=CC(C(F)(F)F)=CN=C1N2CCN(C(C3=CC(S(=O)(C)=O)=CC=C3O[C@@H](C(F)(F)F)C)=O)CC2
Biological Activity: Bitopertin R enantiomer (RG1678 R enantiomer; RO4917838 R enantiomer) is the R-enantiomer of Bitopertin. Bitopertin is a potent, noncompetitive glycine reuptake inhibitor, inhibits glycine uptake at human GlyT1 with a concentration exhibiting IC50 of 25 nM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Bitopertin (R enantiomer) | 95.68% | Bitopertin R enantiomer (RG1678 R enantiomer; RO4917838 R enantiomer) is the R-enantiomer of Bitopertin. Bitopertin is a potent, noncompetitive glycine reuptake inhibitor, inhibits glycine uptake at human GlyT1 with a concentration exhibiting IC50 of 25 nM. | ||||||||||||||||||||
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