847968-58-5
847968-58-5
Chemical Structure
S32212
- CAS No.: 847968-58-5
- Formula:C25H28N4O2
- Molecular Weight:416.52
IUPAC Name: N-(4-methoxy-3-(4-methylpiperazin-1-yl)phenyl)-1,2-dihydro-3H-benzo[e]indole-3-carboxamide
InChIKey: HNWBOBAUHUFDES-UHFFFAOYSA-N
SMILES: O=C(N1CCC2=C1C=CC3=CC=CC=C23)NC4=CC=C(OC)C(N5CCN(C)CC5)=C4
Biological Activity: S32212 is a serotonin type 2C receptor inverse agonist and an 2 adrenoceptor antagonist. S32212 exhibits antidepressant activity and can reduce immobility time in forced-swim test in rats[1].
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S32212 | S32212 is a serotonin type 2C receptor inverse agonist and an 2 adrenoceptor antagonist. S32212 exhibits antidepressant activity and can reduce immobility time in forced-swim test in rats. | |||||||||||||||||||||
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References
- [1]. Dekeyne, A., et al., (2012). S32212, a novel serotonin type 2C receptor inverse agonist/α2-adrenoceptor antagonist and potential antidepressant: II. A behavioral, neurochemical, and electrophysiological characterization. The Journal of pharmacology and experimental therapeutics, 340(3), 765-780. [Content Brief]
