849139-19-1
849139-19-1
Chemical Structure
Gem-C12
- CAS No.: 849139-19-1
- Formula:C21H33F2N3O5
- Molecular Weight:445.50
InChIKey: WIESSGKCXJXYSS-ATZDWAIDSA-N
SMILES: O=C1N=C(NC(CCCCCCCCCCC)=O)C=CN1[C@H]2C(F)(F)[C@H](O)[C@@H](CO)O2
Biological Activity: Gem-C12 is a prodrug of Gemcitabine (HY-17026). Gem-C12 terminates DNA chain elongation, inhibits nucleic acid synthesis and induces Apoptosis. Gem-C12 inhibits the proliferation of glioma cells. Gem-C12 and Honokiol (HY-N0003) exhibit synergistic anti-glioblastoma activity. Gem-C12 can be used in research related to glioblastoma multiforme[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Gem-C12 | 99.48% | Gem-C12 is a prodrug of Gemcitabine (HY-17026). Gem-C12 terminates DNA chain elongation, inhibits nucleic acid synthesis and induces Apoptosis. Gem-C12 inhibits the proliferation of glioma cells. Gem-C12 and Honokiol (HY-N0003) exhibit synergistic anti-glioblastoma activity. Gem-C12 can be used in research related to glioblastoma multiforme. | ||||||||||||||||||||
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