849217-50-1
849217-50-1
Chemical Structure
3-Fluoro-desmethyl-cabozantinib
- CAS No.: 849217-50-1
- Formula:C27H21F2N3O5
- Molecular Weight:505.47
IUPAC Name: N-(3-fluoro-4-((7-hydroxy-6-methoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
InChIKey: DBCXPLBWGBAQKL-UHFFFAOYSA-N
SMILES: O=C(C1(CC1)C(NC2=CC=C(C(F)=C2)OC3=C4C=C(OC)C(O)=CC4=NC=C3)=O)NC5=CC=C(C=C5)F
Biological Activity: 3-Fluoro-desmethyl-cabozantinib is an BCL6 ligand that can be used in the synthesis of PROTACs, such as SJF-8240 (HY-123961)[1]. 3-Fluoro-desmethyl-cabozantinib is also a p38α ligand that can be used to synthesize PROTACs, such as SJFα (HY-114404)[2].
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3-Fluoro-desmethyl-cabozantinib | 3-Fluoro-desmethyl-cabozantinib is an BCL6 ligand that can be used in the synthesis of PROTACs, such as SJF-8240 (HY-123961). 3-Fluoro-desmethyl-cabozantinib is also a p38α ligand that can be used to synthesize PROTACs, such as SJFα (HY-114404). | |||||||||||||||||||||
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