85042-77-9
85042-77-9
Chemical Structure
12a-Hydroxydalpanol
- CAS No.: 85042-77-9
- Formula:C23H24O8
- Molecular Weight:428.43
IUPAC Name: (2R,6aR,12aR)-6a-hydroxy-2-(2-hydroxypropan-2-yl)-8,9-dimethoxy-1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6aH)-one
InChIKey: NSFCLBVWJYYZMR-DNVFCKCGSA-N
SMILES: O[C@@]1([C@](CO2)([H])OC3=C(C[C@@H]4C(C)(O)C)C(O4)=CC=C3C1=O)C(C2=C5)=CC(OC)=C5OC
Biological Activity: 12a-Hydroxydalpanol is a rotenoid cytotoxic agent found in Amorpha fruticosa. 12a-Hydroxydalpanol exerts cytotoxic effects by inhibiting tumor cell proliferation. 12a-Hydroxydalpanol is promising for research of cancers[1][2].
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12a-Hydroxydalpanol | 12a-Hydroxydalpanol is a rotenoid cytotoxic agent found in Amorpha fruticosa. 12a-Hydroxydalpanol exerts cytotoxic effects by inhibiting tumor cell proliferation. 12a-Hydroxydalpanol is promising for research of cancers. | |||||||||||||||||||||
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References
- [1]. Li L, et al. Antitumor agents, 138. Rotenoids and isoflavones as cytotoxic constitutents from Amorpha fruticosa. J Nat Prod. 1993 May;56(5):690-8. [Content Brief]
- [2]. Terada H, et al. Structural elucidation and chemical conversion of amorphispironone, a novel spironone form Amorpha fruticosa, to rotenoids[J]. Chemical and pharmaceutical bulletin, 1993, 41(1): 187-190.
