851378-93-3
Chemical Structure
(±)8(9)-EpETE
Synonym(s): (±)8,9-EEQ; (±)8,9-epoxy Eicosatetraenoic acid
- CAS No.: 851378-93-3
- Formula:C20H30O3
- Molecular Weight:318.45
IUPAC Name: (Z)-7-(3-((2Z,5Z,8Z)-undeca-2,5,8-trien-1-yl)oxiran-2-yl)hept-5-enoic acid
InChIKey: YKIOHMXLFWMWKD-JJUYGIQRSA-N
SMILES: CC/C=C\C/C=C\C/C=C\CC1C(C/C=C\CCCC(O)=O)O1
Biological Activity: Eicosapentaenoic acid (EPA) is converted to epoxyeicosatetraenoic acids (EpETEs) by several cytochrome P450 isoforms. The major product of this epoxygenase pathway, (±)17(18)-EpETE, relaxes vascular and airway smooth muscle by activating large conductance Ca2+-activated K+ (BKCa) channels by directly interacting with BKα channel subunits. (±)8(9)-EpETE is an epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(±)8(9)-EpETE | 99.9% | Eicosapentaenoic acid (EPA) is converted to epoxyeicosatetraenoic acids (EpETEs) by several cytochrome P450 isoforms. The major product of this epoxygenase pathway, (±)17(18)-EpETE, relaxes vascular and airway smooth muscle by activating large conductance Ca2+-activated K+ (BKCa) channels by directly interacting with BKα channel subunits. (±)8(9)-EpETE is an epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo. | ||||||||||||||||||||
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