859518-94-8
859518-94-8
Chemical Structure
T0467
- CAS No.: 859518-94-8
- Formula:C24H26F3N5
- Molecular Weight:441.49
IUPAC Name: (S)-N-(3,5-difluorophenethyl)-4-(2-fluoro-5-((2-methylpiperazin-1-yl)methyl)phenyl)pyrimidin-2-amine
InChIKey: GNYKYGZGDGZPOK-INIZCTEOSA-N
SMILES: FC1=CC=C(CN2[C@H](CNCC2)C)C=C1C3=NC(NCCC4=CC(F)=CC(F)=C4)=NC=C3
Biological Activity: T0467 activates parkin mitochondrial translocation in a PINK1-dependent manner in vitro. T0467 do not induce mitochondrial accumulation of PINK1in dopaminergic neurons. T0467 is a potential compound for PINK1-Parkin signaling activation, and can be used for parkinson's disease and related disorders research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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T0467 | 99.30% | T0467 activates parkin mitochondrial translocation in a PINK1-dependent manner in vitro. T0467 do not induce mitochondrial accumulation of PINK1in dopaminergic neurons. T0467 is a potential compound for PINK1-Parkin signaling activation, and can be used for parkinson's disease and related disorders research. | ||||||||||||||||||||
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