86072-47-1
Chemical Structure
m-APTA
Synonym(s): 5′-S-(3-Aminophenyl)-5′-thioadenosine
- CAS No.: 86072-47-1
- Formula:C16H18N6O3S
- Molecular Weight:374.42
IUPAC Name: (2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-(((3-aminophenyl)thio)methyl)tetrahydrofuran-3,4-diol
InChIKey: NDGWFCVAYOISNC-XNIJJKJLSA-N
SMILES: NC1=CC=CC(SC[C@@H]2[C@@H](O)[C@@H](O)[C@H](N3C=NC(C3=NC=N4)=C4N)O2)=C1
Biological Activity: m-APTA (5'-S-(3-aminophenyl)-5'-thioadenosine) is a selective chemoprotective agent targeting methylthioadenosine phosphorylase (MTAP). m-APTA can be converted into adenine, which is a crucial step in protecting normal cells from the toxicity of nucleobase analogues (NBA). m-APTA is promising for research of MTAP-deficient cancers[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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m-APTA | 99.54% | m-APTA (5'-S-(3-aminophenyl)-5'-thioadenosine) is a selective chemoprotective agent targeting methylthioadenosine phosphorylase (MTAP). m-APTA can be converted into adenine, which is a crucial step in protecting normal cells from the toxicity of nucleobase analogues (NBA). m-APTA is promising for research of MTAP-deficient cancers. | ||||||||||||||||||||
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